A Noninvasive Dynamic Parameter that Helps Clinicians Monitor Fluid Responsiveness in Mechanically Ventilated Patients
Pleth Variability Index (PVi®)
The calculation of PVi (Pleth Variability Index) is based on the measured changes in Pi (Perfusion Index).
In a study of 82 patients undergoing major abdominal surgery, researchers found that PVi-based goal-directed fluid management reduced the volume of intraoperative fluid infused and reduced intraoperative and post-operative lactate levels.5
In a study of 109 patients undergoing colorectal surgery, researchers found that the implementation of an enhanced recovery protocol which included PVi led to improved patient satisfaction and substantial reductions in lengths of stay, complication rates, and costs for patients undergoing both open and laparoscopic colorectal surgery.6
Masimo rainbow SET is a noninvasive monitoring platform featuring Masimo SET® Measure-through Motion and Low Perfusion™ pulse oximetry with the option to measure multiple additional parameters.
Bellamy et al. Br J Anaesth. 2006.
Zimmermann M., et al. Eur J Anaesthesiol. 2010 Jun;27(6):555-61.
Cannesson M., et al. Br J Anaesth. 2008 Aug;101(2):200-6.
Loupec T., et al. Crit Care Med. 2011 Feb;39(2):294-9.
Forget P et al. Anesth Analg. 2010; 111(4):910-4.
Thiele RH et al. J Am Coll Surg. 2015;220:430-443.
Desgranges F.P., et al. Br J Anaesth. 2011 Sep;107(3):329-35.
Cannesson M. J Cardiothorac Vasc Anesth. 2010 Jun;24(3):487-97.
Takeyama M., et al. J Clin Monit Comput. 2011 Aug;25(4):215-21.
Follow the link for available PVi studies.
Technical and clinical factors that may affect PVi include probe malposition, probe site, patient motion, skin incision, spontaneous breathing activity, lung compliance, open pericardium, use of vasopressors or vasodilators, low perfusion index, subject age, arrhythmias, left or right heart failure, and tidal volume.7-9
For professional use. See instructions for use for full prescribing information, including indications, contraindications, warnings, and precautions.
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