Clinical Evidence

Clinical Evidence

Clinical Evidence

 

Clinical Studies

Masimo is passionate about making innovative technologies that give clinicians the tools they need to do what is best for patient care. That's why it is gratifying to see so many clinicians and clinical researchers take the time to evaluate our products and technologies.

Click on the links below to access featured and all available studies that utilize Masimo technologies

Featured Clinical Studies

 

Masimo SET® Pulse Oximetry

 

Accuracy of Masimo SET Pulse Oximetry in Black and White Volunteer Subjects: A Retrospective Review

Barker SJ, Wilson WC. Society of Technology in Anesthesiology. 2022.

Accuracy of Pulse Oximeters Intended for Hypoxemic Pediatric Patients.

Harris BU, Char DS, Feinstein JA, Verma A, Shiboski SC, Ramamoorthy C. Pediatr Crit Care Med. 2016 Apr;17(4):315-20.

Temporal Quantification of Oxygen Saturation Ranges: An Effort to Reduce Hyperoxia in the Neonatal Intensive Care Unit

M J Bizzarro, F Y Li, K Katz, V Shabanova, R A Ehrenkranz and V Bhandari. Journal of Perinatology (2014) 34, 33–38; doi:10.1038/jp.2013.122; published online 26, September 2013

Pulse oximetry with clinical assessment to screen for congenital heart disease in neonates in China: a prospective study.

Zhao Q., Ma X., Ge X, Liu F. , YanW., Wu L., Ye M., Liang X., Zhang J., Gao Y., Jia B., Huang G., The Neonatal Congenital Heart Disease Screening Group. The Lancet, Available online 22 April 2014.

Performance of Three New-Generation Pulse Oximeters during Motion and Low Perfusion in Volunteers.

Shah N., Ragaswamy H.B., Govindugari K., Estanol L. J Clin Anesth. 2012 Aug;24(5):385-91.

Prevention of Retinopathy of Prematurity in Preterm Infants through Changes in Clinical Practice and SpO2 Technology.

Castillo A., Deulofeut R., Critz A., Sola A. Acta Paediatr. 2011 Feb;100(2):188-92.

Impact of pulse oximetry screening on the detection of duct dependent congenital heart disease: a Swedish prospective screening study in 39,821 newborns.

de-Wahl Granelli A., Wennergren M., Sandberg K., Mellander M., Bejlum C., Inganäs L., Eriksson M., Segerdahl N., Agren A., Ekman-Joelsson B.M., Sunnegårdh J., Verdicchio M., Östman-Smith I. BMJ. 2009;Jan 8;338.

More Reliable Oximetry Reduces the Frequency of Arterial Blood Gas Analyses and Hastens Oxygen Weaning after Cardiac Surgery: A Prospective, Randomized Trial of the Clinical Impact of a New Technology.

Durbin C.G. Jr., Rostow S.K. Crit Care Med. 2002 Aug;30(8):1735-40.

Reliability of Conventional and New Pulse Oximetry in Neonatal Patients.

Hay W.W., Rodden D.J., Collins S.M., Melara D.L., Hale K.A., Fashaw L.M. J Perinatol. 2002 Jul-Aug;22(5):360-6.

"Motion-Resistant" Pulse Oximetry: A Comparison of New and Old Models.

Barker S.J. Anesth Analg. 2002 Oct;95(4):967-72.

Pleth Variability Index (PVi®)

 

Use of the pleth variability index in children with obstructive respiratory disease

Demir G, Berksoy E, Bardak Ş, Elibol P, Çiçek A, Özön A, Nalbant T, Gökalp G. Am J Emerg Med. 2022 Mar 17;56:28-32. doi: 10.1016/j.ajem.2022.03.019

A Prospective Observational Study of Plethysmograph Variability Index and Perfusion Index in Predicting Hypotension with Propofol Induction in Noncardiac Surgeries

Thirunelli RK, Nanjundaswamy NH. Anesth Essays Res. 2021;15(2):167-173. doi:10.4103/aer.aer_81_21

The role of perfusion index and plethysmography variability index for predicting dehydration severity in patients with acute gastroenteritis

Emektar E, Dagar S, Uzunosmanoğlu H, Çıkrıkçı Işık G, Çorbacıoğlu ŞK, Çevik Y. Hong Kong J Emerg Med. 2022;29(2):78-83. doi:10.1177/1024907919889488

Perioperative goal-directed fluid management using noninvasive hemodynamic monitoring in gynecologic oncology

Yildiz GO, Hergunsel GO, Sertcakacilar G, Akyol D, Karakaş S, Cukurova Z. Braz J Anesthesiol. 2022 Feb 1:S0104-0014(22)00005-7. doi: 10.1016/j.bjane.2021.12.012

Dynamic variables predict fluid responsiveness in pre-school and school children undergoing neurosurgery: a prospective observational study

Song LL, Geng ZY, Ma W, Liu YF, Wang DX. Transl Pediatr. 2021;10(11):2972-2984. doi:10.21037/tp-21-281

Pleth Variability Index-Directed Fluid Management in Abdominal Surgery under Combined General and Epidural Anesthesia

Yu Y., Dong J., Xu Z., Shen H., Zheng J. J Clin Monit Comput. 2014 Feb 21.

Goal-Directed Fluid Management Based on the Pulse Oximeter-Derived Pleth Variability Index Reduces Lactate Levels and Improves Fluid Management

Forget P, Lois F, de Kock M. Anesth Analg. 2010 Oct;111(4):910-4.

Pleth Variability Index to Monitor the Respiratory Variations in the Pulse Oximeter Plethysmographic Waveform Amplitude and Predict Fluid Responsiveness in the Operating Theatre

Cannesson M., Desebbe O., Rosamel P., Delannoy B., Robin J., Bastien O., Lehot J.J. Br J Anaesth. 2008 Aug;101(2):200-6.

Masimo Patient SafetyNet™

 

Impact of Pulse Oximetry Surveillance on Rescue Events and Intensive Care Unit Transfers: A Before-And-After Concurrence Study.

Taenzer A.H., Pyke J.B., McGrath S.P., Blike G.T. Anesthesiology. 2010 Feb;112(2):282-7.

Postoperative Monitoring – The Dartmouth Experience.

Taenzer A.H., Blike, G. T. APSF Newsletter 2012. Available at:http://www.apsf.org/newsletters/html/2012/spring/01_postop.htm Accessed June 14, 2012.

Continuous Pulse Oximetry Monitoring with Clinician Notification is Associated with Lower Patient Mortality in Post-Surgical/Medical Patients

Carlson J. Respiratory Care 2013; 58 (10):1784

Total Hemoglobin (SpHb®)

 

Continuous hemoglobin measurement during frontal advancement operations can improve patient outcomes

Saracoglu, A., Abdullayev, R., Sakar, M. et al. J Clin Monit Comput. 2022. doi:10.1007/s10877-022-00813-5

Continuous and noninvasive hemoglobin monitoring reduces red blood cell transfusion during neurosurgery: a prospective cohort study.

Awada WN, Mohmoued MF, Radwan TM, Hussien GZ, Elkady HW. J Clin Monit Comput. 2015 Feb 4. [Epub ahead of print] PubMed PMID: 25649717.

Trending and Accuracy of Noninvasive Hemoglobin Monitoring in Pediatric Perioperative Patients

Patino M, Schultz L, Hossain M, Moeller J, Mahmoud M, Gunter J, Kurth CD. Anesth Analg. 2014 Jul 17. [Epub ahead of print] PubMed PMID: 25036374.

Accuracy of a Continuous Noninvasive Hemoglobin Monitor in Intensive Care Unit Patients.

Frasca D., Dahyot-Fizelier C., Catherine K., Levrat Q., Debaene B., Mimoz O. Crit Care Med. 2011 Oct;39(10):2277-82.

The Accuracy of Noninvasive and Continuous Total Hemoglobin Measurement by Pulse CO-Oximetry in Human Subjects Undergoing Hemodilution.

Macknet M.R., Allard M., Applegate R.L., Rook J. Anesth Analg. 2010 Dec;111(6):1424–6.

Acoustic Respiration Rate (RRa®)

 

The Accuracy, Precision and Reliability of Measuring Ventilatory Rate and Detecting Ventilatory Pause by Rainbow Acoustic Monitoring and Capnometry

Ramsay M.A.E., Usman M., Lagow E., Mendoza M., Untalan E., De Vol, E. Anesth Analg 2013

Accuracy of respiratory rate monitoring using a non-invasive acoustic method after general anaesthesia.

Mimoz O., Benard T., Gaucher A., Frasca D., Debaene B. Br J Anaesth. 2012 May;108(5):872-5.

Accuracy of Acoustic Respiration Rate Monitoring in Pediatric Patients

Patino M., Redford D.T., Quigley T.W., Mahmoud M., Kurth C.D., Szmuk P. Paediatr Anaesth. 2013 Sep 3.

Carboxyhemoglobin (SpCO®)

 

Accuracy of Noninvasive Multiwave Pulse Oximetry Compared With Carboxyhemoglobin From Blood Gas Analysis in Unselected Emergency Department Patients.

Roth D., Herkner H., Schreiber W., Hubmann N., Gamper G., Laggner A.N., Havel C. Ann Emerg Med. 2011 Jul;58(1):74-9.

Noninvasive Pulse CO-Oximetry Expedites Evaluation and Management of Patients with Carbon Monoxide Poisoning.

Hampson N.B. Am J Emerg Med. 2012 Nov;30(9):2021-4.

Methemoglobin (SpMet®)

 

Severe Methemoglobinemia Detected by Pulse Oximetry.

Annabi E.H., Barker S,J. Anesth Analg. 2009;108:898–9.

Regional Oximetry (O3®)

 

Absolute and Trend Accuracy of a New Regional Oximeter in Healthy Volunteers During Controlled Hypoxia.

Redford D, Paidy S, Kashif F. Anesth Analg. 2014 Dec; 119(6):1315-1319. PubMed PMID: 25405692.

SedLine® Brain Function Monitoring

 

Impact of Processed Electroencephalography in Cardiac Surgery: A Retrospective Analysis

Jarry S, Halley I, Calderone A, Momeni M, Deschamps A, Richebé P, Beaubien-Souligny W, Denault A, Couture EJ. J Cardiothorac Vasc Anesth. 2022. doi:10.1053/j.jvca.2022.03.030

Processed Multiparameter Electroencephalogram-Guided General Anesthesia Management Can Reduce Postoperative Delirium Following Carotid Endarterectomy: A Randomized Clinical Trial

Xu N, Li LX, Wang TL, Jiao LQ, Hua Y, Yao DX, Wu J, Ma YH, Tian T, Sun XL. Front Neurol. 2021 Jul 12;12:666814. doi: 10.3389/fneur.2021.666814

Titration of Delivery and Recovery from Propofol, Alfentanil, and Nitrous Oxide Anesthesia.

Drover D.R., Lemmens H.J., Pierce E.T., Plourde G., Loyd G., Ornstein E., Prichep L.S., Chabot R.J., Gugino L. Anesthesiology 2002; 97:82–9.

Masimo Capnography and Gas Monitoring

 

Feasibility of portable capnometer for mechanically ventilated preterm infants in the delivery room

Hotta M, Hirata K, Nozaki M, Mochizuki N, Hirano S, Wada K. Eur J Pediatr. 2022;181(2):629-636. doi:10.1007/s00431-021-04246-1

Evaluation of a Transportable Capnometer for Monitoring End-Tidal Carbon Dioxide.

Hildebrandt T., Espelund M., Olsen K.S. Anaesthesia. 2010 Oct;65(10):1017-21.

Masimo softFlow™

 

Nasal high-flow versus noninvasive ventilation in patients with chronic hypercapnic COPD.

Bräunlich et al. Int J Chron Obstruct Pulmon Dis 2019;(14):1411-1421.

Reductions in dead space ventilation with nasal high flow depend on physiological dead space volume: metabolic hood measurements during sleep in patients with COPD and controls.

Biselli et al. Eur Respir J 2018;51:1702251.

Nasal high-flow therapy reduces work of breathing compared with oxygen during sleep in COPD and smoking controls: a prospective observational study.

Biselli et al. J Appl Physiol (1985). 2017;122(1):82-88.

Nasal highflow improves ventilation in patients with COPD.

Bräunlich J et al.
Int J Chron Obstruct Pulmon Dis. 2016;(11):1077-1085.

The use of the trademark Patient SafetyNet is under license from University HealthSystem Consortium.

Masimo devices with SpHb, SpCO and/or SpMet monitoring are not intended to replace laboratory blood testing. Blood samples should be analyzed by laboratory instruments prior to clinical decision-making.

Duplicate abstracts or publications are excluded

This section is intended to provide access to clinical studies conducted using Masimo noninvasive technologies, parameters, and products. We cannot guarantee that all published clinical studies, abstracts and research are listed here. To view individual clinical studies please click on the appropriate tab.

Some uses of the manufacturer’s devices described in the information may not have been approved or cleared by the FDA. See manufacturer labeling for the indications in the product’s cleared indications for use statement.

Clinical evidence is provided to illustrate the performance and accuracy of Masimo technologies. Federal law restricts Masimo devices for medical uses to sale by or on the order of a physician.

PLCO-004090/PLM-10296H-0920